Ursolic and Oleanolic Acids: Plant Metabolites with Neuroprotective Potential

Ursolic and oleanolic acids are secondary plant metabolites that known to be involved in the defence system against water loss pathogens. Nowadays these triterpenoids also regarded as potential pharmaceutical compounds there is mounting experimental data either purified or triterpenoid-enriched extracts exert various beneficial effects, including anti-oxidative, anti-inflammatory anticancer, on model systems of both human animal origin. Some those effects have been linked ability ursolic modulate intracellular antioxidant inflammation cell death-related pathways. Therefore, our aim was review current studies distribution plants, bioavailability pharmacokinetic properties their derivatives, discuss neuroprotective vitro vivo.